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Dihydrocodeine 30mg Dosage Guide (UK)

Dihydrocodeine 30mg Dosage Guide (UK)

Dihydrocodeine 30mg is the standard-release strength most commonly prescribed across the UK. This guide covers adult dosing, timing, maximum daily dose, and when to step up to slow release.

Adult dose

  • One tablet (30mg) every 4 to 6 hours as needed for pain
  • Maximum 180mg in any 24-hour period (i.e. 6 tablets)
  • Take with or after food to reduce nausea
  • Swallow whole with water; do not crush or chew

Onset and duration

  • Onset: 30 to 60 minutes
  • Peak effect: around 2 hours
  • Duration: 4 to 6 hours

When to take it

Dihydrocodeine 30mg is best for as-needed pain control β€” a fresh post-op wound, a fracture, a flare of sciatica, severe period pain. If you find yourself needing a tablet every 4 hours around the clock for more than a few days, that’s the moment to consider stepping up to 60mg slow release instead.

Can you take it with paracetamol or ibuprofen?

Yes β€” both are common, safe UK pairings. See paracetamol with dihydrocodeine and dihydrocodeine and ibuprofen.

What not to combine

  • Alcohol (see dihydrocodeine and alcohol)
  • Other opioids (codeine, tramadol, morphine)
  • Benzodiazepines (diazepam, lorazepam)
  • Pregabalin or gabapentin without medical advice
  • Sleeping tablets (zopiclone, zolpidem)

All of these combinations increase the risk of dangerous respiratory depression.

Missed dose

If you miss a dose, take it as soon as you remember unless it’s close to your next dose. Never double-dose.

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