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Dihydrocodeine Side Effects — Full UK Guide

Dihydrocodeine Side Effects — Full UK Guide

Like every opioid analgesic, dihydrocodeine carries a predictable set of side effects. Most are mild and settle within a few days as your body adapts.

Very common (more than 1 in 10)

  • Constipation — start a stool softener (lactulose, Movicol) on day one if you’ll be taking it more than 2–3 days
  • Drowsiness — don’t drive or operate machinery until you know how it affects you
  • Nausea — usually settles within 3–5 days; take with food
  • Dry mouth

Common (up to 1 in 10)

  • Headache
  • Dizziness, especially on standing
  • Mild itching
  • Sweating
  • Mood change (mild euphoria or low mood)

Less common

  • Difficulty passing urine
  • Visual disturbance
  • Slow heart rate

Rare but serious — seek urgent help

  • Difficulty breathing or very slow breathing
  • Severe confusion or hallucinations
  • Allergic reaction (rash, swelling of face/lips, wheezing)
  • Severe abdominal pain

Call 999 or go to A&E immediately if any of these occur.

Side effects of 30mg specifically

See our dedicated 30mg side-effects breakdown.

What about long-term use?

Prolonged daily use causes physical dependence — your body adapts and stopping suddenly produces withdrawal. Read our withdrawal and tapering guide before stopping any long course.

Reducing side effects

  • Take with food
  • Stay well hydrated
  • Start laxatives early
  • Use the lowest effective dose for the shortest time

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