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Dihydrocodeine and Breastfeeding — What to Know

Dihydrocodeine and Breastfeeding — What to Know

A brief overview is in our pregnancy guide; this article focuses specifically on breastfeeding.

How much passes into breast milk?

Dihydrocodeine and its active metabolite both pass into breast milk in small but measurable amounts — typically 1–2% of the maternal dose. For a healthy full-term baby this is usually too little to cause harm from a single dose.

When is it riskier?

  • Premature babies
  • Newborns under 4 weeks old (immature liver)
  • Mothers who are “ultra-rapid metabolisers” via CYP2D6 (rare)
  • Daily dosing rather than occasional dosing

Safer alternatives while breastfeeding

For mild pain, paracetamol is the first choice. For moderate pain, paracetamol + ibuprofen. Only step up to dihydrocodeine if those have failed.

Practical tips if you must take it

  • Take the lowest effective dose
  • Take it immediately after a feed
  • Watch your baby for unusual sleepiness, poor feeding, or breathing changes
  • Stop and seek medical advice if anything seems off

See also

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